Airlines that offer direct flights make getting from Italy to the US easy and faster. Direct flights save you time, make your trip more comfortable, and lower stress. Choosing the right airline is essential whether you go on vacation, for business, or to see family. Today, we will talk about the best airlines that fly directly from Italy’s most significant cities to many cities in the United States. This guide will help you find the best choices based on routes, comfort, and services.

Alitalia (ITA Airways)
Rome to New York JFK
There are direct flights from Rome Fiumicino to New York JFK on ITA Airways, which used to be called Alitalia. People traveling for work and pleasure like this route. The airline has flights daily, so you can choose how to travel. People enjoy comfortable seats, entertainment, and meals based on Italian food.
Milan to Miami
ITA Airways also has direct flights from Milan Malpensa to Miami International Airport. This is an excellent option for people going to Florida. Modern planes and focused customer service staff are part of the airline’s service on this route. With a flight time of about 10 hours, this is one of the fastest ways to get from Italy to Miami.
Rome to Boston
ITA Airways has a direct flight from Rome to Boston Logan International Airport for people going to the northeastern United States. This route is excellent for people who want to go to Boston for business or to see colleges or historical places. The airline keeps safety and comfort at a high level.
American Airlines
Milan to New York JFK
American Airlines offers a daily direct trip from Milan Malpensa to New York JFK. This route is perfect for both work and vacation travelers. Business class, premium economy, and economy are some of the seating choices that the airline offers. Passengers can enjoy free entertainment and Wi-Fi services aboard.
Rome to Philadelphia
American Airlines connects Rome Fiumicino to Philadelphia by direct flight. Philadelphia is a key gateway to other places in the USA. The airline ensures a smooth trip with excellent customer service and timely departures. This route is beneficial for travelers with onward connections.
Venice to Chicago
Another choice from American Airlines is the direct flight from Venice Marco Polo Airport to Chicago O’Hare. This exceptional service is excellent for people traveling in the summer and going to the Midwest. This long distance route is taken by vast body planes, which make the trip more comfortable.
Delta Air Lines
Rome to Atlanta
You can direct Delta Air Lines to Hartsfield Jackson Atlanta International Airport from Rome. Athens is a significant hub for Delta, which makes it easy to get to other US cities. The airline has excellent amenities, such as Delta Studio for entertainment and various food choices.
Milan to New York JFK
Many people fly Delta’s direct path from Milan to New York JFK when they want to travel across the Atlantic. The company is known for being on time and taking good care of its customers. People can pick from different classes, such as Delta One for a more luxurious experience.
Venice to Detroit
Delta also makes direct trips from Venice to Detroit Metropolitan Airport at certain times of the year. This road is handy for people in the north of the United States or Canada. The airline’s strong network makes it easy and smooth to travel to other places.
United Airlines
Rome to Newark
United Airlines has a direct trip from Rome to Newark Liberty International Airport. Newark is close to New York City, which makes it a good option to JFK. United has good customer service, comfortable seats, Wi-Fi, and various meals.
Milan to Chicago
There is also a direct United Airlines flight from Milan to Chicago O’Hare. People traveling for work or pleasure in the central United States often take this route. The airline makes sure that service is quick and connections are good.
Naples to Newark
From Naples Capodichino Airport to Newark, United Airlines has direct flights during certain times of the year. This is an excellent choice for tourists in southern Italy. The flight skips layovers so that people can get to the US faster.
Emirates (via codeshare with Italian carriers)
Bologna to New York JFK (Codeshare with ITA)
Emirates does not have planes that fly straight from Italy to the US, but it shares flights with ITA Airways from Bologna to New York JFK. Even though these trips are advertised as Emirates, they are run by ITA. Emirates’ booking method and customer service are suitable for passengers.
Florence to Los Angeles (Codeshare with ITA and US airlines)
Through codeshare agreements, people traveling from Florence can get direct flights to Los Angeles. There may be a short stopover in the US on these routes, but they are usually advertised as seamless links. Emirates makes booking easier and gives you points for being loyal.
Rome to San Francisco (Codeshare with United)
Because Emirates and United Airlines share a code, people flying from Rome can book a direct trip to San Francisco. This choice lets you leave Italy and easily reach the West Coast of the United States.
Lufthansa (via partnership routes)
Milan to Washington D.C. (Through codeshare)
United Airlines and Lufthansa work together to offer direct flights from Milan to Washington, D.C. Even though Lufthansa does not fly the planes, its technology is used for booking and customer service. This gives Lufthansa loyalists more choices and peace of mind.
Venice to Houston (Partnered flights)
Lufthansa also helps set up partner trips between Houston, Texas, and Venice, Italy. Some of these may be straight segments made possible by codeshare agreements. Coordinated flight schedules and Lufthansa’s help worldwide are suitable for travelers.
Rome to Denver (Seasonal service via partner)
Another journey that can be booked through Lufthansa’s platform with partner airlines is from Rome to Denver. People traveling for business or pleasure to the western part of the USA will find these trips helpful.
Seasonal and Charter Airlines
Neos Air (based in Italy)
Neos Air has direct trips from Milan to New York and Fort Lauderdale during certain times of the year. These flights are popular around the holidays and do not cost much money. Neos’ base prices include basic services, comfortable seats, and checked bags.
La Compagnie (Boutique airline)
La Compagnie sometimes offers special charter trips from Italy to the US. This is especially true during busy times or events. They only offer services in business class and provide a high class experience at reasonable prices.
Air Italy (formerly active, now ceased)
Air Italy used to have direct trips to the United States, but they no longer do. But keeping up with the news is essential because new providers may emerge.
Tips for Booking Direct Flights from Italy to the USA
Compare prices early
It is best to check flight prices as early as possible to get the best deals. Compare flights on services that let you, and sign up for fare alerts. You can save money and be sure of a seat if you buy a ticket ahead of time.
Check baggage and seat options
Each flight has its own rules about bags and seats. Some cheap tickets might not let you choose your seats or check bags. To avoid extra fees, make sure you look over these details before you book.
Look for nonstop options
Not every direct flight goes straight through. Some may stop in another US city on the way to their final location. Always check the flight information twice to ensure the route stops.
Conclusion
More than ever, it is easy to find companies that fly directly from Italy to the USA. ITA Airways, American Airlines, Delta, and United are just a few big airlines that fly directly between important towns in Italy and cities in the United States. You can fly from Rome, Milan, Venice, or Naples; several choices exist. Compare flights, know what services are included, and book early for the best deals. Picking the right flight can make your trip more fun and less stressful, and help you get where you are going faster. Plan your next trip with this guide, and have a smooth, straight flight from Italy to the US.